ive been to chile a long time ago but it was mainly a business trip so unfortunately i didnt get to see the place for what its worth. but i would suggest going with a tour group because i dont think, south america is really a well established touristy area like europe but im sure it can be just as fun if you know the area and what exactly you going to do there. besides that, i also know there's famous waterfall which i think is in argentina which is right by santiago. oh and while your down there, try guarana. its good stuff that you cant get here in the states for some reason.